All articlesPain & Recovery

Medication After Knee Surgery

Dr CR Oosthuizen 3 min read

Paracetamol, an anti-inflammatory, a short course of opioid, and blood-thinning prophylaxis.

A typical regimen: paracetamol regularly for 2–3 weeks, an anti-inflammatory tablet for 2 weeks (if your stomach and kidneys tolerate it), a short course of an opioid such as tramadol for breakthrough pain in the first 5–10 days, and a blood-thinner — usually a small daily tablet — for 2–6 weeks.

Anti-nausea tablets and a laxative are prescribed alongside opioids because constipation is almost universal otherwise. Your existing chronic medication is continued unless specifically stopped before surgery.

Stop the opioid as soon as you can manage with paracetamol and the anti-inflammatory. Pain that requires escalating opioids beyond two weeks is not normal — let us know.

Next Step

Request an Appointment with Dr Oosthuizen

Reading about your knee is a great start. The next step is an individual assessment — share your details and we'll be in touch within one business day.

Handled in line with POPIA. Not for medical emergencies — call 10177 instead.

Educational content only. Prefer to speak first? Try the Knee Check or contact the rooms directly.

Consulting: Mon · Tue · Thu (AM)